Given scientific fact as input, generate the question from this fact such that it can be answered from the input.
--------
Question: Multiple genes mutations is usually necessary to develop cancer.

Answer: What is usually necessary to develop cancer?


Question: Endoscopes are used to explore the body through various orifices or minor incisions.

Answer: Endoscopes are used to explore the body through various orifices or these?


Question: Homes and transportation use half (fifty) percent of all energy in the u.s.

Answer:
Homes and transportation use what percent of all energy in the u.s.?