Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

Example Input: Cells have four cycles.
Example Output: How many cycles do cells have?

Example Input: Protists are thought to be the oldest eukaryotes.
Example Output: What is thought to be the oldest eukaryotes?

Example Input: Hagfishes have a skull made of cartilage.
Example Output:
Hagfishes have a skull made of what?