TASK DEFINITION: Given scientific fact as input, generate the question from this fact such that it can be answered from the input.
PROBLEM: Reptiles typically reproduce sexually.

SOLUTION: How do reptiles typically reproduce?

PROBLEM: Pleiotropic effects causes symptoms associated with sickle-cell disease.

SOLUTION: What causes symptoms associated with sickle-cell disease?

PROBLEM: During inhalation phase of breathing does the pressure inside the lungs drops to below atmospheric pressure.

SOLUTION:
During what phase of breathing does the pressure inside the lungs drops to below atmospheric pressure?